From Standards to Metamodeling Architecture

Growth of knowledge in post-genomic biology and systems biology requires integration of data and biologists need methods and tools that offer such an integrated view

Rather than building a single structure for representing integrated data, it can be relied on MDE methods and tools (more details on MDE here) to build architectures of representation.
Such integration architectures can be based on standards and ontologies that are widely recognised and used within the biological community (more details on standards here).

A metamodeling architecture based on biological standards

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The proposed architecture is organised in a hierarchy so that models of two given applications are linked to the same reusable model or metamodel that describes the consensus shared within the application domain.

Reference

# Terrasse MN and Roux M. Metamodeling architectures for complex data integration in biology. (2010) Journal of Biomedical Engineering and Technology, Special issue Warehousing and Mining Complex Data: Applications to Biology and Medicine. Vol 3 (1/2), 22-42.(PDF 520 MB)